Royal Air Force Typhoon fighter aircraft have operated alongside French warplanes in a coordinated attack targeting an underground arms cache in Syria employed by the IS group, per a report from the UK Ministry of Defence.
The facility, located using intelligence, was assessed as storing arms and explosives, the statement said, and was located in mountainous terrain just above the ancient city of Palmyra in Syria's central region.
"Our aircraft employed precision-guided Paveway IV munitions to target a several entry passages providing entry to the depot... initial indications suggest the strike was effective," the MoD said.
There was no evidence of any civilian casualties in the attack late on Saturday and each participating jet returned safely, the MoD added.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
IS - alternatively referred to as the so-called Islamic State - enforced militant control over large swathes of Syria and Iraq prior to its 2019 collapse.
"This operation shows our UK leadership, and resolve to operate in unison with our partners, to eliminate any re-emergence of IS and their harmful and extremist ideologies in the region," Britain's Defence Chief the Defence Secretary stated.
UK warplanes have carried out overwatch operations over Syrian airspace to "prevent any efforts to regroup" of IS subsequent to its routing at the Baghuz confrontation in 2019, the MoD reported.
"I extend gratitude to all the members of our armed forces who took part in this mission for their skill and their bravery," he said. "Including them were a great many UK service members on duty over Christmas and New Year. This action, to remove terrorist threats who endanger our way of life, shows how British military are prepared to act, all year round, ensuring Britain's security at home and influential overseas."
Last December, the US military executed what it termed a "large-scale strike" targeting IS targets in the country, subsequent to an attack killed two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations says IS still maintains between 5,000 and 7,000 militants in Iraq and Syria.